Nanodispersions

Tharwat F. Tadros

Published by De Gruyter 2016

Nanodispersions

Tharwat F. Tadros

In the series De Gruyter Textbook

https://doi.org/10.1515/9783110290349

Overview
Contents

About this book

General introduction - Definition of nanodispersions (nanosuspensions, nanoemulsions, swollen micelles or microemulsions, liposomes and vesicles) and their size range. General description of their colloid stability. Main advantages of nanodispersions and their industrial applications.
Preparation of nanosuspensions by top-up process - Nucleation and growth and control of particle size distribution. Factors determining the formation of narrow particle size distribution. Role of surfactants and polymers. Preparation of nano-polymer colloids (lattices) by emulsion and dispersion polymerization. Factors affects the stability of nanosuspensions.
Preparation of nanosuspensions by bottom down process - Dispersion of preformed particles in liquids and the need of a wetting agent. Break-up of aggregates and agglomerates by application of high speed stirrers. Reduction of particle size by application of intense energy (microfluidization or bead milling). Maintenance of the colloid stability of the resulting particles. Reduction of Ostwald ripening.
Industrial applications of nanosuspensions - Application in pharmacy to enhance bioavailability, Application in sunscreens for UV protection. Application in paints and coatings.
Preparation of nanoemulsions by the use of high pressure homogenisers - Principles of emulsion formation and the role of the emulsifier. Selection of emulsifiers. Methods of emulsification and prevention of coalescence during emulsification. Origin of colloid stability of nanoemulsions. Prevention of Ostwald ripening
Low energy methods for nanoemulsion preparation - The phase inversion composition method and the role of mixing the surfactant with oil and water. The phase inversion temperature method for preparation of nanoemulsions. Preparation of nanoemulsions by dilution of microemulsions.
Practical examples of nanoemulsions and their industrial application - Nanoemulsions based on non-ionic surfactants and the role of the hydrophilic-lipophilic balance. Effect of oil solubility on the stabilityof nanoemulsions. Nanoemulsions based on polymeric surfactants. Applications in pharmacy and cosmetics.
Swollen micelles or microemulsionsDefinition of microemulsions and their size range. Thermodynamic definition of microemulstions. Theories of microemulsion formation and stability. Characterisation of microemulsions using scattering, conductivity and NMR rechniques.
Formulation of microemulsions and their industrial applications - Distinction between microemulsions and macroemulsions. Formulation of oil/water and water/oil microemulsions. Selection of emulsifiers for microemulsions. Application of microemulsions in tertiary oil recovery.
Liposomes and vesicles - Formation of multilamellar lipid layers (liposomes) by dispersion of lipids in water. Formation of unilamellar vesicles by sonication of the liposomes. Factors responsible for stabilisation of liposomes and vesicles. Use of block copolymers to enhance the stability of vesicles. Applications of liposomes and vesicles in pharmacy and cosmetics.

A concise and accessible overview of the nanodispersions (nanosuspensions, nanoemulsions and microemulsions).
Highly practical in approach, introducing briefly the science, followed by industrial applications.

Author / Editor information

Tharwat F. Tadros, Wokingham, UK.

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Reviews

"Die verschiedenen Kapitel bieten eine moderne Einführung in interessante Themen, und sie sind so aufgebaut, dass sie auch ohne große Vorkenntnisse zur raschen und aktuellen Information dienen. Die Texte sind von hoher wissenschaftlicher Qualität, und sie enthalten interessante Beispiele aus verschiedenen Bereichen der Kolloidchemie."
H. Rehage in: Chem. Ing. Tech. 90.8 (2018), 1104

Topics

Frontmatter Publicly Available Download PDF	I
Preface Requires Authentication Unlicensed Licensed Download PDF	V
Contents Publicly Available Download PDF	XI
1. Nanodispersions – general introduction Requires Authentication Unlicensed Licensed Download PDF	1
2. Colloid stability of nanodispersions Requires Authentication Unlicensed Licensed Download PDF	11
3. Ostwald ripening in nanodispersions Requires Authentication Unlicensed Licensed Download PDF	33
4. Preparation of nanosuspensions by the bottom-up process Requires Authentication Unlicensed Licensed Download PDF	45
5. Preparation of nanosuspensions using the top-down process Requires Authentication Unlicensed Licensed Download PDF	77
6. Industrial application of nanosuspensions Requires Authentication Unlicensed Licensed Download PDF	95
7. Nanoparticles as drug carriers Requires Authentication Unlicensed Licensed Download PDF	131
8. Preparation of nanoemulsion using high pressure homogenizers Requires Authentication Unlicensed Licensed Download PDF	189
9. Low energy methods for preparation of nanoemulsions and practical examples of nanoemulsions Requires Authentication Unlicensed Licensed Download PDF	217
10. Swollen micelles or microemulsions and their industrial applications Requires Authentication Unlicensed Licensed Download PDF	239
Index Requires Authentication Unlicensed Licensed Download PDF	281

(Deutsch)

Language: English
Publisher: De Gruyter
Audience: Pharmaceutical Chemists, Materials Scientists, Chemists, Students.
Pages
- Front matter: 14
- Main content: 298
Illustrations
- Illustrations: 100
- Coloured Illustrations: 50
- Line drawings: 150
- Images: 50
- Tables: 50
Keywords: Materialwissenschaften; Nanotechnologie; Oberflächen; Kolloide

eBook

Published: December 14, 2015
ISBN: 9783110290349

Paperback

Published: November 27, 2015
ISBN: 9783110290332