Heart failure (HF) hospitalizations and rehospitalizations account for a large proportion of healthcare expense in the United States. Guidelines suggest interprofessional team care can be effective in managing patients with HF and preventing readmissions. The primary objective of this systematic review was to examine the evidence for effectiveness of interprofessional care teams to reduce readmissions in patients with HF. Most of the studies showed reduction in readmission rates after implementation of interprofessional team intervention in HF care.