cyclooxygenase-1

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Noun

cyclooxygenase-1 - an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys; "an unfortunate side effect of NSAIDs is that they block Cox-1"

Cox-1

Cox, cyclooxygenase - either of two related enzymes that control the production of prostaglandins and are blocked by aspirin

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References in periodicals archive ?

Ginger suppresses prostaglandin synthesis through inhibition of cyclooxygenase-1 and cyclooxygenase-2 thereby its usefulness in arthritis was understood.

Anti-inilammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats

Crypt stem cell survival in the mouse intestinal epithelium is regulated by prostaglandins synthesized through cyclooxygenase-1. J.

Cytotoxic and pro-oxidative effects of Imperata cylindrica aerial part ethyl acetate extract in colorectal cancer in vitro

Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs.

Optimizing NSAID management

Levine, "Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer," Journal of the National Cancer Institute, vol.

The inhibitory effect of a novel polypeptide fraction from Arca subcrenata on cancer-related inflammation in human cervical cancer Hela cells

3D model from PDB ID: 1PTH was obtained from SWISS-MODEL repository for cyclooxygenase-1 (COX-1) (http://www.rcsb.org/pdb/explore/explore .do?structureId=1pth) and 3D model from PDB ID: 6COX for cyclooxygenase-2 (COX-2) [13].

Binding energy calculation of Patchouli alcohol isomer cyclooxygenase complexes suggested as COX-1/COX-2 selective inhibitor

Identification and functional analysis of cyclooxygenase-1 as a molecular target of boswellic acids.

Tylenol treats the blues

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis.

Activation of diverse eicosanoid pathways in osteoarthritic cartilage a lipidomic and genomic analysis

Expression of cyclooxygenase-1 and 2 in naturally occurring canine cancer.

The use of COX-2 inhibitor in the treatment of transitional cell carcinoma of urinary bladder in dogs--review/Uso de inibidores de COX-2 no tratamento do carcinoma de celulas de transicao de bexiga em caes--revisao/Uso de inhbidores de COX-2 en el tratamiento del carcinoma de celulas de transiociones de vejiga en perros--revision

If they ingest a cyclooxygenase-1 inhibitor, they develop asthma symptoms, rhinorrhea, periorbital edema, urticaria, pruritus, angioedema, anaphylaxis, or other symptoms.