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Volume 6, Issue 6, June – 2021 International Journal of Innovative Science and Research Technology

ISSN No:-2456-2165

Aqueous Chemosis: Rare Complication in Nephrotic


Syndrome in Adults
A.Benjaafar , K.Sebti(1) ; L.Benamar (1) ; L. El Kaissoumi (2)
N .Ouzeddoun ; R. Bayahia (1) ;T.Bouattar (1). (2)
Ophthalmology A, Specialties Hospital,
(1):
Nephrology Department, Ibn Sina Hospital Mohamed V University
Mohamed V University Rabat, Morocco
Rabat, Morocco

Abstract:- A 42-year patient with nephrotic syndrome Biomicroscopic ophthalmologic examination revealed
was presented because of bilateral chemosis. The the presence of bilateral aqueous chemosis (Fig:1), non-
diagnosis was based on physical examination , In the inflammatory, more pronounced in the left eye, The anterior
biological assessment, there is a hypo albuminemia, segment was calm, and the fundus recovered papillae with
nephrotic proteinuria , and an active urinary sediment, sharp contours of normal staining, physiological excavation,
with renal function was preserved. The and the macula was unremarkable in ODG.
anatomopathological study of kidney biopsy puncture
(KBP) objectified: extra capillary glomerulonephritis . The anatomopathological study of KBP objectified:
The course was marked by the regression of the aqueous extra capillary glomerulonephritis with endocapillary lesions
chemosis after the treatment of glomerulonephritis . with linear deposits of IGg and C3.

Keywords:- Chemosis; Nephrotic Syndrome, Extracapillary The diagnosis of extra capillary glomerulonephritis was
Glomerulonephritis . retained, and led to the administration of a bolus of
methylprednisolone, followed by 6 boluses of
I. INTRODUCTION cyclophsphamide, a diuretic treatment and an anti-thrombotic
treatment, with good progress. clinico-biological and in
Aqueous chemosis or white chemosis is a rare and particular a regression of bilateral chemosis.
reversible complication of nephrotic syndrome. We report the
case of a 42-year-old patient presenting with nephrotic III. DISCUSSION
syndrome and in whom the ophthalmologic examination
found bilateral aqueous chemosis falling within the Chemosis is a rare and unusual complication of
anasarchus picture in which the patient presented. nephrotic syndrome. [1

II. CASE REPORT A similar case has been reported in the literature in a
15-year-old child with severe nephrotic syndrome [2].
A 42-year-old patient, with no pathological history, was
presented to the emergency room in a state of anasark Aqueous chemosis, or conjunctival edema, may be
associating a bilateral aqueous chemosis more marked on the inflammatory or non-inflammatory. Non-inflammatory
left. chemosis is most often secondary to an allergic reaction.

General clinical examination found edema of the lower Frequently asymptomatic, as is the case with our
limbs, pleural effusion syndrome, with high blood pressure. patient. However, it can manifest as irritation, tearing,
pruritus or sometimes even diplopia.
In the biological assessment, there is a hypoproteinemia
at 35g / l, deep hypo albuminemia at: 17g / l, nephrotic As part of the syndrome, it seems that chemosis is
proteinuria: 15g / 24h and an active urinary sediment, with secondary to fluid retention secondary to hypoprotidemia. No
renal function was preserved, as well as the C3, C4 fraction local treatment would be indicated and the regression of
of the complement which was normal, the immunological chemosis would be done in parallel with the regression of the
workup was negative. generalized edematous syndrome [1].

IJISRT21JUN613 www.ijisrt.com 818


Volume 6, Issue 6, June – 2021 International Journal of Innovative Science and Research Technology
ISSN No:-2456-2165
IV. CONCLUSION

Aqueous chemosis in nephrotic syndrome is a rare but


benign complication. It would be secondary to the fluid
retention due to hypoprotidemia, and no local treatment is
indicated, the regression of chemosis would be concomitant
with the disappearance of the clinical-biological nephrotic
syndrome.

Fig 1 : aqueous chemosis on admission

REFERENCES

[1]. Garibotto G, Giannoni M, Salvatore FComplications of


nephrotic syndrome. G Ital Nefrol 20,2003, (1):49–60.
[2]. Jankauskiene, A. & Buteikiene, I. Eur J Pediatr ,2009,
168:507. https://doi.org/10.1007/s00431-008- 0795-x.

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