Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

Nat New Biol. 1971 Jun 23;231(25):232-5. doi: 10.1038/newbio231232a0.
No abstract available

MeSH terms

  • Animals
  • Arachidonic Acids / metabolism
  • Aspirin / pharmacology
  • Biological Assay
  • Chromatography, Thin Layer
  • Colon / drug effects
  • Guinea Pigs
  • Indomethacin / pharmacology
  • Lung / metabolism
  • Prostaglandins / analysis
  • Prostaglandins / biosynthesis*
  • Prostaglandins / pharmacology
  • Rats
  • Salicylates / adverse effects
  • Salicylates / pharmacology*
  • Salicylates / therapeutic use
  • Stomach / drug effects

Substances

  • Arachidonic Acids
  • Prostaglandins
  • Salicylates
  • Aspirin
  • Indomethacin