Abstract
A new benzofuran glycoside, masutakeside I (1) and a new C10 acetylenic acid, masutakic acid A (2) were isolated from the fruiting bodies of the fungus Laetiporus sulphureus var. miniatus. Their structures were established by spectroscopic and chemical methods. The known compounds 3-6 were also obtained and identified as egonol, demethoxyegonol, egonol glucoside and egonol gentiobioside. Some of these compounds exhibited cytotoxicity against Kato III cells.
MeSH terms
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Alkynes
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Antineoplastic Agents / isolation & purification*
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Antineoplastic Agents / pharmacology*
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Benzofurans / chemistry*
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Benzofurans / isolation & purification
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Drug Screening Assays, Antitumor
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Fatty Acids, Unsaturated / chemistry*
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Fatty Acids, Unsaturated / isolation & purification
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Glycosides / chemistry*
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Hydrolysis
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Magnetic Resonance Spectroscopy
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Polyporaceae / chemistry*
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Spectrometry, Mass, Fast Atom Bombardment
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Spectrophotometry, Ultraviolet
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Tumor Cells, Cultured
Substances
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Alkynes
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Antineoplastic Agents
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Benzofurans
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Fatty Acids, Unsaturated
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Glycosides
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masutakeside I
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masutakic acid A
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2-hexadecynoic acid