Abstract
An outbreak of EHV1 abortions occurred at a riding school in The Netherlands in 1991. Seven of twelve pregnant mares aborted, and another foal died at 8 days of age. Six abortions occurred within 12 days in March after an initial abortion on 8 February. Four mares delivered live foals. Virological examination of four aborted foals revealed an EHV1 infection. Serological results for paired sera from 17 horses suggested, that the initial abortion on 8 February was the index case, and probably caused the other six abortions. The index case could well have been caused by reactivation of latent virus induced by transport stress. The laboratory results are discussed in the light of the present knowledge of the pathogenesis and epidemiology of EHV1 abortion.
MeSH terms
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Abortion, Veterinary / epidemiology
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Abortion, Veterinary / virology*
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Animals
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Antibodies, Monoclonal
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DNA, Viral / analysis
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DNA, Viral / blood
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Deoxyribonuclease BamHI / chemistry
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Disease Outbreaks / veterinary*
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Electrophoresis, Agar Gel / veterinary
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Enzyme-Linked Immunosorbent Assay / veterinary
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Female
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Fetus / virology
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Fluorescent Antibody Technique, Indirect / veterinary
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Herpesviridae Infections / blood
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Herpesviridae Infections / epidemiology
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Herpesviridae Infections / veterinary*
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Herpesvirus 1, Equid / genetics
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Herpesvirus 1, Equid / pathogenicity*
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Horse Diseases / epidemiology
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Horse Diseases / virology*
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Horses
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Male
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Neutralization Tests / veterinary
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Polymerase Chain Reaction / veterinary
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Pregnancy
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Pregnancy Outcome / veterinary
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RNA, Viral / chemistry
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RNA, Viral / isolation & purification
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Stress, Physiological / veterinary
Substances
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Antibodies, Monoclonal
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DNA, Viral
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RNA, Viral
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Deoxyribonuclease BamHI