Levoketoconazole

Levoketoconazole

Levoketoconazole is one of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing’s syndrome.

Systematic name

1-[4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one

Brand name(s)

Recorlev

Therapeutic Category

Cushing's syndrome (CS)

Suitable Formulations

Solid

Approvals

USDMF Exclusive for US market

EU-WC

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