Tranexamic Acid Powder, also known as tranexamic acid γ- Aminobutyric acid is a very important amine substance that is converted from alanine. The extraction sources of tranexamic acid are quite extensive, and common methods include natural extraction and synthetic extraction. Natural extraction is mainly extracted from food, such as cocoa beans, sugarcane, soybeans, etc. in South America; Synthesis and extraction are usually prepared using alanine as the raw material through chemical reactions. The main specifications of tranexamic acid are 99%, usually in two forms: powder and tablet. The powder specification is usually 25kg/barrel, with a white powder appearance that is easily soluble in water; The tablet specification is 250mg/tablet or 500mg/tablet, which can be taken orally and is easy to carry and use.
Tranexamic acid is a synthetic derivative of the amino acid lysine. It is used to treat or prevent excessive blood loss during surgery and in various other medical conditions. It is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, by binding to specific sites of both plasminogen and plasmin, a molecule responsible for the degradation of fibrin, a protein that forms the framework of blood clots.
| {Product Name}: | Tranexamic Acid |
| {Other Name}: | Amstat |
| {CAS No.}: | 1197-18-8 |
| {Einecs No.}: | 214-818-2 |
| {Appearance}: | White Crystalline Powder |
| {Speccification}: | 99% |
| {Molecular formula}: | C8H15NO2 |
| {MOQ}: | 1kg |
| {Application}: | Pharmaceutical |
Specification:
| Item | Standard | Results |
| Characteristics | White or almost white, crystalline powder | White crystalline powder |
| Solubility | Freely soluble in water and in glacial acetic acid, pratically insoluble in acetone and 96% alcohol | Complies |
| Identification | Infrared absorption atlas consistent with the contrast atlas | Complies |
| Clarity and color | Solution should clarify and colorless | Complies |
| Ph | 7.0-8.0 | 7.4 |
| Related substances Liquid chromatography (2.29) | Impurity A: ≤0.1% | 0.012% |
| Impurity B: ≤0.2% | 0.112% |
| Any other impurity: ≤0.1% | <0.034% |
| All other impurity: ≤0.2% | <0.034% |
| Chlorides | ≤140ppm | <140ppm |
| Heavy Metals | ≤10ppm | <10ppm |
| Loss on drying | ≤0.5% | 0.3% |
| Sulphate Ash | ≤0.1% | 0.04% |
| Assay | 99.0%~101.0% | 99.8% |
| Conclusion | Complies with BP2013 specification. |
(1). Skin Whitening
Tranexamic Acid ,a mechanism of work that the validity of the whitening, not only can play excellent cleaning effect, the further reduce melanin, fade melanin generation spots, can prevent ultraviolet ray to skin damage and play excellent whitening effect! So the more stable, not easy the acid by temperature environmental damage, without excitant etc many advantages, and to ensure the it in the whitening and don't stimulate the skin.
(2). Lowering blood sugar:
Wholesale Tranexamic Acid can promote the secretion of insulin and the action of anti glucagon hormones, thereby lowering blood sugar levels. It can also improve the efficiency of glucose uptake and utilization by cells. Tranexamic acid has a significant effect on the prevention and treatment of diabetes.
(3). Antibacterial and anti-inflammatory:
Tranexamic Acid Powder has strong antibacterial and anti-inflammatory effects. It can inhibit the growth and reproduction of various bacteria, especially with good inhibitory effects on common Gram positive and negative bacteria.
(4). Beauty and skincare:
Bulk Tranexamic Acid can effectively inhibit the formation and deposition of melanin, and to some extent slow down skin pigmentation and aging. Chuanming acid can also enhance the skin's moisturizing ability, promote skin metabolism, and make the skin more delicate and smooth.
(5). Health care:
Tranexamic Acid powder bulk is widely used in medicine for antibacterial, anti-inflammatory, antiviral, and anti-tumor purposes. In addition, hyaluronic acid can also regulate cholesterol, improve cardiovascular function, protect the liver, resist oxidation, and have various health benefits for human health.
Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver, vascular and large orthopedic procedures. Its oral form is now being evaluated for use in outpatient conditions involving heavy bleeding.
Trauma
Tranexamic acid has been found to decrease the risk of death in people who have significant bleeding due to trauma. However, it may actually increase the risk of death due to bleeding if administered more than 3 hours after the injury.
Heart Surgery
Tranexamic acid is commonly used in cardiac surgery, both with and without cardiopulmonary bypass. It replaces aprotinin.
Orthopedic Surgery
Tranexamic acid is used in orthopedic surgery to reduce bloodloss. It is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced.
Menstrual Bleeding
Used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. A recent study showed patients treated with tranexamic acid are more likely to develop thrombosis and necrosis in their fibroids, and may result in pain and fever.
Dentistry
Tranexamic acid is used in dentistry in the form of a 5% mouth rinse after extractions or surgery in patients with prolonged bleeding time, e.g. from acquired or inherited disorders.
Other usesIn obstetrics, tranexamic acid is used after delivery to reduce bleeding, often with syntocinon/oxytocin and fundal massage.
In Hemophilia
Tranexamic acid is also useful in the treatment of bleeding as a second line treatment after factor VIII in patients (e.g. tooth extraction).
Whitening Effect
Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%
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