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Volume 7, Issue 3, March – 2022 International Journal of Innovative Science and Research Technology

ISSN No:-2456-2165

Analysing and Comparing the Prevalence of Common


Medical Conditions Literature Review
Michael Halim
University of Salford, MSc Biomedical Science,
Greater Manchester, United Kingdom

Abstract:- Notable studies have pointed out the growing vaccines would be effective enough to prevent the different
prevalence rate for common medical conditions. Among emerging strains of the virus.
these featured in the studies include zoonotic diseases,
retinitis pigmentosa, cleft lip, and palate, which affect Besides Covid-19, Halim, and Halim (2019), Dong et
millions of people worldwide. In addition, other scholars al. (2016), and Halim believe diabetes is among the most
have expounded on diabetes, cancer, the outbreak of prevalent diseases. The studies show that diabetes keeps
Covid-19 and ultimately demonstrated that how the increasing in different areas of the world, with Type 2
world responds to the pandemic has consequences. As Diabetes Mellitus being the most common type of insulin-
such, to uphold a state of normalcy, it is recommended related disease. In this case, the body’s resistance to insulin
that academia, governments, and the health industry is caused by the disruption of the dissemination of glucose
work together to develop and test vaccines speedily. to the surrounding tissues due to vasodilation of the blood
Moreover, herd immunity, which was also applicable in vessels. Similarly, Halim and Halim (2020) established that
fighting measles, rubella, and influenza, should always the mortality associated with Type 2 Diabetes Mellitus is
be sought as an effective and ideal preventive strategy. mainly due to hyperglycaemia, a core factor that brings
about inflammation. Both inflammation and oxidative stress
I. INTRODUCTION contribute to the pathogenesis of type 2 diabetes mellitus. In
addition, Xie et al. (2021) contend that reactive oxygen
Many scholars have articulated the prevalence of species are involved in the onset and progression of
common medical conditions. Some studies have explained diabetes. The study’s experiment shows that the redox state
cancer with reference to hemangioblastomas which occurs at affects blood glucose levels in diabetic rats, and oxidative
any age and causes different symptoms like tumours that stress can potentially aggravate diabetes.
appear or disappear depending on the location and size of
the tumour (Halim and Halim, 2020). Some studies have Halim and Halim (2020) show that cardiometabolic
discussed diabetes, more specifically, Type 2 Diabetes, complications can be caused by an individual’s lifestyle,
which is the most common type of insulin-related disease. such as smoking and poor diet. This is also the case,
Halim et al. (2021) also explained that zoonotic diseases are according to a study by Li et al. (2016) that aimed to find
more prevalent in urban areas. On the other hand, studies out why antioxidants inhibit cancer cells. Like Halim et al.
have recently focused on Covid-19 with a keen interest in (2021), the study established that NAC interventions cause a
how herd immunity can be achieved. With this in mind, the difference in the telomerase activities in cancer and normal
literature review provides an insight into the various medical cells subject to an imbalance in the redox homeostasis.
conditions shaping the scope of scientific knowledge. Expanding on the statement, another study denoted that
hemangioblastomas occur at any age with different
II. LITERATURE REVIEW symptoms like the tumours appearing or disappearing
depending on the location and size of the tumour (Halim,
Studies by Halim et al. (2021) and Zhang et al. Halim, and Trivosa, 2019). In the same breadth, Halim and
(2018)show the prevalence of various medical conditions. Halim, Halim, and Trivosa (2019) discussed the role of the
Halim et al. (2021) found that zoonotic diseases, especially P53 tumour suppressor gene. Halim said that the P53
in urban settings, have increased over the years. Zhang et al. tumour suppressor gene is widely known to damage nuclear
(2018) established that retinitis pigmentosa, a heterogeneous metabolism in the body and increase the number of chronic
retinal disorder, is more prevalent today, affecting roughly 2 illnesses.
million people worldwide. Also, Trivosa, Halim, and
Yongyan explained that cleft lip and palate remain a In addition, another study denoted that the NBAS gene
common congenital malformation in the maxillofacial and plays a significant role in retinal homeostasis, making it
oral regions. On the other hand, since 3000 B.C, there have indispensable to closely observe and investigate ocular
been various global pandemics, including the most recent abnormalities among SOPH patients (Thong et al., 2021).
Covid-19 outbreak, that has come in handy in proving that Thus, the different types and the overwhelming number of
how the world responds to the pandemic has consequences cancer cases across the globe have prompted scholars to
(Halim, 2021). In agreement, a recent report by Halim pursue more effective therapies than traditional treatments.
(2021) denotes that to return to normalcy, different For instance, Halim (2021) proposes PARP inhibitors such
governments, academia, and the health industry must work as Talazoparib, Olaparib, and Rucaparib that use the concept
together in developing and testing vaccines speedily. of synthetic lethality to kill tumour cells. On the other hand,
However, considering that the SARS-CoV-2 keeps according to Halim et al. (2021), unlike cancers, the
mutating, there is significant doubt whether the available treatment of degenerative mitral valve diseases, which have

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Volume 7, Issue 3, March – 2022 International Journal of Innovative Science and Research Technology
ISSN No:-2456-2165
been increasing in prevalence, involves surgical procedures [7.] Halim M, Inuwa MF, Umenne CA, Israel KA,
such as Conventional Surgery (CVS) and Minimally Standard operating Protocol (SOP) of Haematopoietic
Invasive Surgery whose outcomes in terms of effectiveness Stem Cells Enumeration, J Bioscience and Biomedical
differ. Patients who have undergone MIS have low Engineering. 2020; 1-5, https://doi.org/10.47485/2693-
postoperative infection rates and can return early to their 2504.1030
normal activities, in addition to incurring low costs. [8.] Halim, M. PARP (poly (ADP)-ribose polymerase)
Inhibitors–Application of Synthetic Lethality Concepts
Molecular analysis of biomolecules is applicable in in Cancer Treatments. Cancer, 14(2), 237-246.
many research areas encompassing genetic disorders [9.] Halim, M., AlSayegh, M., Umenne, C. A., Vadithya,
(Halim, 2020). This is true considering the various studies P., Panicker, S. V., Israel, K. A., & Halim, A. (2021).
that have proven this assertion, although with considerable Analyzing and comparing the impacts and outcomes of
precautionary measures. To begin with, Yuan et al. (2019) two different types of surgeries–Minimally Invasive
and Gong et al. (2019) suggested that it was not suitable to Surgeries (MIS) and Conventional Surgeries (CVS) on
switch patients in SSRI mono therapy with early non- patients suffering from Degenerative Mitral Valve
improvement in anxiety and insomnia. According to Halim, Diseases. Journal of Health Care and Research, 2(1), 1.
Halim, and Trivana (2020), herd immunity, having been [10.] Halim, A., Bhekharee, A. K., Feng, M., Cheng, X., &
applied in the fight against diseases such as measles, rubella, Halim, M. (2021). Prevalence of Zoonotic Pathogens
and influenza remains the most suitable practical preventive in Domestic and Feral Cats in Shanghai, with Special
measure. Nevertheless, studies by Halim, Halim, and Reference to Salmonella. Journal of Health Care and
Trivosa (2020) and Halim, Halim, and Tjhin (2021) contend Research, 2(1), 1.
that there is a need for more research on the efficacy of [11.] Halim, M., & Halim, A. (2019). The effects of
specific treatments and therapies. inflammation, aging and oxidative stress on the
pathogenesis of diabetes mellitus (type 2
III. CONCLUSION diabetes). Diabetes & metabolic syndrome: clinical
To conclude, the literature has outlined and discussed research & reviews, 13(2), 1165-1172.
the increasing prevalence of various common medical [12.] Halim M., Halim A., Molecular Analysis of
conditions over the years and the measures and treatments biomolecules pertaining to the diagnosis of a human
that have been implemented to counter them. Undoubtedly, genetic disorder: Lesch-Nyhan Syndrome, Adv
research on more effective treatments is required to reduce Biomed Res Innov. 2020; 3:7 doi:
their prevalence, so as to reduce the mortality rate, improve 10.4172/abri.1000128.
patients’ overall quality of life, and relieve the healthcare [13.] Halim, M., & Halim, A. (2020). Commentary: the
and economic strain on the world as a whole. effects of inflammation, aging, and oxidative stress on
the pathogenesis of Type II Diabetes. Journal of Health
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Volume 7, Issue 3, March – 2022 International Journal of Innovative Science and Research Technology
ISSN No:-2456-2165
[20.] Halim, M., Halim, A., & Trivosa, V. (2019).
Symptoms, Diagnosis and Treatment of
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